What's Inside
Three Evidence-Based Protocols, Built to Work Together
Most longevity routines are a cabinet full of disconnected supplements. The Longevity Stack is three physician-prescribed therapies chosen to hit aging from different angles — energy production, brain function, and cellular senescence.
Methylene Blue
5 mg · 60 tablets
A pharmaceutical-grade mitochondrial electron cycler. At low doses it helps shuttle electrons in the cellular energy chain — supporting ATP production, mental clarity, and focus.
Low-dose methylene blue improved memory retrieval and increased activity in memory-related brain regions in a controlled fMRI study.Rodriguez et al., Radiology →
Rapamycin Cream
0.05% · Face & Hands
A topical mTOR-pathway therapy applied to the face and the backs of the hands — the areas that show age first. Targets the cellular senescence that drives visible aging.
In a randomized human trial, topical rapamycin reduced the senescence marker p16INK4A, increased collagen VII, and improved clinical signs of aging skin. Chung et al., GeroScience →
NAD+ Self-Injectable
200 mg/ml · 6 mL
Subcutaneous NAD+ delivers the coenzyme directly into your system, bypassing the digestive losses that limit oral supplements — supporting energy, DNA repair, and healthy aging.
NAD+ precursor therapy raised NAD+ levels and improved mitochondrial function in controlled human trials. Yoshino et al., Science Translational Medicine →
Why Stack Them
One Coordinated Strategy Against Aging
Each therapy targets a different, well-studied hallmark of aging. Together they cover more ground than any single product.
01 · ENERGY
Power Your Mitochondria
NAD+ and methylene blue both support the mitochondrial machinery that converts nutrients into usable cellular energy — the engine behind stamina and focus.
02 · REPAIR
Support Cellular Maintenance
NAD+ fuels the sirtuin and PARP pathways involved in DNA repair, while topical rapamycin targets the senescent cells that accumulate as skin ages.
03 · APPEARANCE
Look As Vital As You Feel
Rapamycin cream works where aging shows first — the face and hands — complementing the internal energy and repair the injectables support.
What Patients Look For
The Outcomes That Matter
Sustained Energy
Mitochondrial support for fewer afternoon crashes.
Mental Clarity
Support for focus, memory, and sharpness.
Healthier-Looking Skin
Targeting visible aging on face and hands.
Recovery & Vitality
Cellular support for how you feel day to day.
Cellular Longevity
Pathways tied to DNA repair and senescence.
One Simple Routine
Three protocols, coordinated and delivered together.
The Science
Grounded in Peer-Reviewed Research
Each component of the stack is informed by published human and mechanistic studies from leading journals.
Radiology · 2016
Methylene Blue Modulates Memory and Brain Connectivity
A controlled functional-MRI study found low-dose methylene blue improved memory retrieval and increased activity in brain regions tied to attention and memory.
GeroScience · 2019
Topical Rapamycin Reduces Markers of Senescence in Human Skin
A randomized trial showed topical rapamycin lowered the senescence protein p16INK4A, raised collagen VII, and improved clinical signs of skin aging.
Science Translational Medicine · 2021
NAD+ Precursor Improves Muscle Insulin Sensitivity
A randomized, placebo-controlled human trial demonstrated improved muscle insulin sensitivity and enhanced mitochondrial function with NAD+ repletion.
Cell Metabolism · 2022
NAD+ Repletion Counteracts Features of Aging Muscle
Boosting NAD+ enhanced oxidative metabolism and protective capacity in aging human skeletal muscle, supporting performance and healthy aging.
How It Works
Simple, Doctor-Led Process
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Acquire & Complete Intake
Reserve your stack and fill out a short medical questionnaire online.
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Physician Review
Dr. David Mahjoubi reviews your submission and confirms the stack is right for you.
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Delivered to Your Door
Your stack is compounded by a licensed pharmacy and shipped — with shipping included.
The Complete Bundle
The Longevity Stack
$450
- Methylene Blue 5 mg — 60 tablets
- Rapamycin Cream 0.05% — facial & top-of-hand application
- NAD+ Self-Injectable 200 mg/ml — 6 mL
- Physician review — by Dr. David Mahjoubi
- Free shipping — delivered to your door
Questions
Frequently Asked
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Three physician-prescribed therapies: Methylene Blue 5 mg (60 tablets), Rapamycin Cream 0.05% for the face and backs of the hands, and NAD+ Self-Injectable 200 mg/ml (6 mL). The complete bundle is $450 with shipping included.
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Yes. These are compounded medications that require a prescription. After you complete the online intake, Dr. David Mahjoubi reviews your health history and, if appropriate, sends the prescription to a licensed compounding pharmacy that ships your stack to you.
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Methylene blue is taken orally as directed, rapamycin cream is applied topically to the face and tops of the hands, and NAD+ is a small subcutaneous injection. Full instructions are included, and Dr. David can answer questions during review.
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Many patients report improved energy and clarity within the first couple of weeks, while skin and longevity-related benefits build gradually over weeks of consistent use. Individual results vary.
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When prescribed by a licensed physician and sourced from a licensed compounding pharmacy, each component has an established safety profile. Your medical history is individually reviewed before anything is prescribed. Tell your physician about all medications and conditions.
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We are unable to ship injectable NAD+ to California residents due to California State Board of Pharmacy regulations. We ship to most other U.S. states.
These statements have not been evaluated by the Food and Drug Administration. Compounded formulations are not FDA-approved as finished products and are prepared by licensed compounding pharmacies under physician direction. This page is for informational purposes only and is not medical advice; it does not diagnose, treat, cure, or prevent any disease. Individual results vary. A prescription is issued only after physician review of your medical history, and these therapies may not be appropriate for everyone — including those who are pregnant or breastfeeding, or who have certain medical conditions. We are unable to ship injectable NAD+ to California residents due to state Board of Pharmacy regulations.
